Open Systems Pharmacology

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Reliable, powerful and easy-to-use modeling & simulation tools for pharmaceutical and other life-sciences applications. Qualified and accepted by the scientific community including academia, regulatory agencies and industry. Available free to everyone.

Essentials

Download OSP Suite

Explore the full functionality of the OSP suite. PBPK, PBPK/PD, QSP – the OSP Suite gives you the flexibility to build it all without having to start from scratch.

Forum

Have your questions answered or provide answers to others. The Forum is a great way to stay up-to-date on the community buzz around OSP.

Documentation

Need to find out how to use a feature? Looking to understand the inner workings of the model? Here you’ll find the extensive OSP manual and qualification documents.

News & Release

Save the Date: OSP Community Conference 2026

In Beerse, Antwerp September 24th and 25th

Open Systems Pharmacology Suite - Version 12 Update 2

We are pleased to announce the new release of the OSP Suite Version 12 Update 2 which is now available for download.

WORKSHOP AT ACOP COLORADO.

Join ESQlabs at the ACoP Conference in Colorado Building Scalable PBPK-QSP Models - Modularization in MoBi for OSP Suite V12.

Ready to take the plunge? Download

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2.3. Developmental Stages & Sensitive Periods

5.1. Medical Therapies

The Future of the Field

The future of animal behavior and veterinary science is bright and technologically driven. Research : When looking for any event or

2. Practice Cooperative Care

Teach your pet that handling is good. Use treats to simulate an exam: touch the paws, look in the ears, lift the lips. This is behavioral conditioning that allows veterinary science (preventative exams) to happen safely and accurately.

9. Case Example (Short)

Signalment: 4-year-old MN Labrador retriever
Complaint: Sudden growling at family members
Initial thought: Behavioral aggression
Workup: Orthopedic exam → hip dysplasia (pain-induced aggression)
Outcome: Pain management + behavior modification → resolution in 2 weeks

6. The Role of the Veterinary Behaviorist

Publications & Models

Models

Glucose Insulin Model

Scientifically exciting for diabetes researchers. Technically exciting for everyone with PBPK models of glucose, insulin, and glucagon coupled through non-mechanistic PD as well as systems pharmacology PD models.

Publications

Journal Publications

Growing list of scientific journal publications that relates to OSP or describes work with PK-Sim® or MoBi®. Add your own contributions and label them or others appropriately to further grow and structure this database.

Take a look at all our models Browse

Management Team

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